CERIC Center of Excellence for Research on Inflammation and Cardiovascular disease

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Atherosclerosis Research Unit Department of Medicine, Solna Karolinska Institutet

Center for Molecular Medicine and Department of Cardiology Karolinska University Hospital

Phone +46 8 524 868 39

Group members

Andersson, Ida
Postdoc

Bäckdahl, Liselotte
Postdoc

Bereczky Veress, Biborka
Project Manager

Bäcklund, Johan
Senior Researcher

Ge, Changrong
Postdoc

Guerard, Simon
PhD Student
 
Förster, Florian
Postdoc

Haag, Sabrina
PhD Student

Holmdahl, Rikard
Professor
Vaartjes, Daniëlle
PhD Student

Wernersson, Evelina
Technician

Winter, Susann
Postdoc

Yang Min
Postdoc

Yao Mattisson, Angel
Administrator

Yau, Anthony
PhD Student

Urbonaviciute, Vilma
Postdoc

Xu, Bingze
Biochemist

Zhong, Jianghong
Postdoc
Olsson, Lina
Geneticist

Palestro, Carlos
Technician

Palestro, Kristina
Technician

Raposo, Bruno
Postdoc

Saxena, Amit
Postdoc

Sareila, Outi
Postdoc

Tuncel, Jonatan
Postdoc

van den Berg, Susanne
Lab Engineer

Wing, Kajsa
Assistant Professor
Johannesson, Martina
Postdoc

Khmaladze, Ia
PhD Student

Klocke, Katrin
PhD Student

Kutty Selva, Nandakumar
Associate Professor

Lönnblom, Erik
PhD Student

Mondoc, Emma
Lab Engineer

Norin, Ulrika
PhD Student



Rikard Holmdahl

In order to obtain basic biological knowledge explaining the development of autoimmune diseases such as rheumatoid arthritis and multiple sclerosis we are using experimental animal models. The ultimate goal is to identify prognostic markers and to establish new therapies for these diseases. We have set out the following more specific goals:
  1. To identify the most important genes that control relevant animal models for rheumatoid arthritis and multiple sclerosis. In particular we aim to understand the genes determining the pathogenic events transforming the disease into chronicity.
  2. To understand the role of MHC class II genes in explaining the immune specificity of autoimmune disease.
  3. To use the animal models not only for understanding the basic mechanism of autoimmune disease but also as models for developing new diagnostic, preventive and therapeutic strategies for autoimmune diseases such as rheumatoid arthritis and multiple sclerosis.

Research interactions with CERIC

  • To develop an animal models and genetic platform for studies of pathogenic mechaisms in chronic inflammatory diseases
  • To investigate in depth the genetic contorl of oxiudation pathways controlling autoimmunity and inflammation
  • To validate new preventive and therapeutic possibilities for the future prevention and treatrment of chronic inflammatory diseases