CERIC Center of Excellence for Research on Inflammation and Cardiovascular disease

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Department of Medicine, Division of Rheumatology at Karolinska University Hospital

Phone +46 8 517 733 48

Group members

Senior Scientists

Andor Pivarcsi
Enikö Sonkoly
Liv Eidsmo
Pernilla Nikamo

Research Assistants/post-docs

Ning Xu
Warangkana Lohcharonenkal

Graduate Students

Stanley Cheuk
Florian Meisgen
Josefin Lysell
Elisa Martini

Technical Staff

Kerstin Bergh
Helena Griehsel
Maria Lundqvist

Mona Ståhle

Psoriasis is a common, hereditary and clinically highly heterogenous disease where the genetic background in combination with environmental triggers determine disease phenotype, severity and likely response to treatment. The ultimate cause for psoriasis is still unknown. Using a Stockholm cohort of individuals diagnosed within maximum 12 months of disease onset, we study disease triggers, phenotype/genotype correlation, clinical course, comorbidities and response to treatment. Healthy individuals matched for sex and age serve as control. Even though skin is the main target organ, psoriasis is today considered as a systemic disease with significant co-morbidities such as arthritis and cardiovascular disease. Our cohort with carefully phenotyped patients coupled with an extensive biobank provide serves as our main research tool. Another line of research is the role for the human antimicrobial cathelicidin peptide LL-37 in chronic inflammation and as a driver for autoimmunity.

Research interactions with CERIC

  • Immunobiology of chronic inflammation.
  • Psoriasis , the metabolic syndrome and cardiovascular co-morbidity.
  • Common genes between psoriasis, MS and atherosclerosis.
  • The role of LL-37 in chronic inflammation and autoimmunity.